Takebe.Lab

ABOUT US​

VISION

My Medicine

From Disease- to Humanity-care

Takebe Lab will move medicine into the new dimension so-called “My Medicine”, by bringing research and innovation dedicated to evolving, alleviating and treating humanity today and in the future. We are committed to nurture the respect, integration, visualization and sharing in our diverse community.

MISSION

Imagination that Creates

We respect the “zero” field, where science has not fully explored yet today. Creation from zero is always a risk and takes tremendous courage to commit and accept the outcome. This ability to make a conscious, risky, decision is unique to humanity, and we, as scientist, should exploit it.

1. Imagine, Small.


2. Involve, Friends.


3. Inspire, People.

Think weird, crazy, small idea, constantly, and ideate the simplest experiment. 

Define what you cannot do, then find collaborators. Interact people with different culture and expertise. 

Amplify your small idea, and visualize its potential and promise that inspires.

WHERE WE ARE?

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CINCINNATI CHILDREN’S HOSPITAL MEDICAL CENTER (CCHMC)
TOKYO MEDICAL AND DENTAL UNIVERSITY (TMDU)
TAKEDA-CiRA program (T-CiRA)
YOKOHAMA CITY UNIVERSITY (YCU-CDC)

WHAT WE DO?

The goal of our laboratories is to conduct basic research and discovery to commit to next-gen medicine with four major areas of interests include: 

(1) model and manipulate humanity in model systems
(2) understand variations and deviations of humanity  
(3) prevent, alleviate and treat diseases of humanity

Some of our core capability includes:

  • human stem cell culture
  • animal model system
  • gene editing and genomics
  • robotics and automation
  • drug screening
  • deep learning
  • design and art

CCHMC

CCHMC Lab investigates the mechanisms of organogenesis and pathogenesis in humans, translated into in-a-dish engineering principles for complex organoid system.

Key references
Cell Metabolism, 2019
Nature, 2019
Science, 2019

TMDU

TMDU Lab studies the genetic basis of pathogenesis to understand human variations.
We are committed to develop regenerative medicine therapeutics. 

Key references
Nature, 2013
Cell Stem Cell, 2015
Nature, 2017

T-CiRA

T-CiRA Lab is composed by academicians and pharama-scientists from Takeda.
We run vascularized liver organoid based drug discovery program for intractable disease.

Key references
Nature Medicine, 2020
Dev Biol, 2018

YCU-CDC

YCU-CDC Lab explores the potential of the design and art approaches for improving humanity and medicine.

Major attempts include street medical school and gamification lab. 

Key references
https://streetmedicalschool.com/en/
https://www.astellas.com/jp/en/news/20861
http://y-cdc.org/portfolios/

WHo WE ARE?

Alumni

Teacher, Autumn Ferguson, Calvary Christian School, KY
Assistant professor, Hiroyuki Koike, Nhon Medical Univ, Japan
Research fellow, RanRan Zhang, Rutgers Univ, NYC
PhD student, Kirsten Giesbrecht, UNC, NC

Assistant professor, Takahisa Matsuzaki, Saitama Univ, Japan
Researcher, Yuqi Cai, NYC
Research assistant, Mihika Sharma, CCHMC, OH