Takebe Lab will move medicine into the new dimension so-called “My Medicine”, by bringing research and innovation dedicated to evolving, alleviating and treating humanity today and in the future. We are committed to nurture the respect, integration, visualization and sharing in our diverse community.
MISSION
Imagination that Creates
We respect the “zero” field, where science has not fully explored yet today. Creation from zero is always a risk and takes tremendous courage to commit and accept the outcome. This ability to make a conscious, risky, decision is unique to humanity, and we, as scientist, should exploit it.
1. Imagine, Small.
2. Involve, Friends.
3. Inspire, People.
Think weird, crazy, small idea, constantly, and ideate the simplest experiment.
Define what you cannot do, then find collaborators. Interact people with different culture and expertise.
Amplify your small idea, and visualize its potential and promise that inspires.
WHERE WE ARE?
CINCINNATI CHILDREN’S HOSPITAL MEDICAL CENTER (CCHMC) TOKYO MEDICAL AND DENTAL UNIVERSITY (TMDU) TAKEDA-CiRA program (T-CiRA) YOKOHAMA CITY UNIVERSITY (YCU-CDC)
WHAT WE DO?
The goal of our laboratories is to conduct basic research and discovery to commit to next-gen medicine with four major areas of interests include:
(1) model and manipulate humanity in model systems (2) understand variations and deviations of humanity (3) prevent, alleviate and treat diseases of humanity
Some of our core capability includes:
human stem cell culture
animal model system
gene editing and genomics
robotics and automation
drug screening
deep learning
design and art
CCHMC
CCHMC Lab investigates the mechanisms of organogenesis and pathogenesis in humans, translated into in-a-dish engineering principles for complex organoid system.
T-CiRA Lab is composed by academicians and pharama-scientists from Takeda. We run vascularized liver organoid based drug discovery program for intractable disease.
Key references Nature Medicine, 2020 Dev Biol, 2018
YCU-CDC
YCU-CDC Lab explores the potential of the design and art approaches for improving humanity and medicine.
Major attempts include street medical school and gamification lab.
Teacher, Autumn Ferguson, Calvary Christian School, KY Assistant professor, Hiroyuki Koike, Nhon Medical Univ, Japan Research fellow, RanRan Zhang, Rutgers Univ, NYC PhD student, Kirsten Giesbrecht, UNC, NC
Assistant professor, Takahisa Matsuzaki, Saitama Univ, Japan Researcher, Yuqi Cai, NYC Research assistant, Mihika Sharma, CCHMC, OH