PUBLICATIONS
Article
2020
Polygenic architecture informs potential vulnerability to drug-induced liver injury
Nature Medicine | in press
Koido et al. revealed genetically defined hepatocyte vulnerability mechanisms to currently unpredictable drug induced liver injury supported by cell-, organoid- and patient-level datasets.
Koido M, Kawakami E, Fukumura J, Noguchi Y, Ohori M, Nio Y, Nicoletti P, Aithal G, Daly, A, Watkins P, Anayama H, Dragan Y, Shinozawa T & Takebe T
Methods in Cell Biology | 22 May
Wendy elaborated a human liver organoid culture protocol based on Ouchi et al. Cell Metabolism paper in 2019.
Wendy L. Thompson, Takanori Takebe
bioRxiv | Posted 21 April
Han et al. identified unexpected diversity in mesoderm-derivatives during early foregut organogenesis. This study is highly collaborative work with Aaron Zorn group and Mitsuru Morimoto group at RIKEN.
Lu Han, Praneet Chaturvedi, Keishi Kishimoto, Hiroyuki Koike, Talia Nasr, Kentaro Iwasawa, Kirsten Giesbrecht, Phillip C Witcher, Alexandra Eicher, Lauren Haines, Yarim Lee, John M Shannon, Mitsuru Morimoto, James M Wells, Takanori Takebe, Aaron M Zorn
European Journal of Cardio-Thoracic Surgery | 7 April
Okabe et al., in collaboration with thoracic surgeons at Kyoto, extended fetal organ bud transplantation approach towards acute lung injury protection in mouse model.
Ryo Okabe, Toyofumi F Chen-Yoshikawa, Akihiko Yoshizawa, Tsuyoshi Hirashima, Masao Saito, Hiroshi Date, Takanori Takebe
2019
Cell Metabolism | May 30
Ouchi et al. established a method to generate multicellular organoid models of inflammation and fibrosis that can be used for genetic steatohepatitis modeling.
Ouchi, R., Togo, S., Kimura, M., Shinozawa, T., Koido, M., Koike, H., Thompson, W., Karns, R. A., Mayhew, C. N., McGrath, P. S., McCauley, H. A., Zhang, R. R., Lewis, K., Hakozaki, S., Ferguson, A., Saiki, N., Yoneyama, Y., Takeuchi, I., Mabuchi, Y., Akazawa, C., Yoshikawa, H. Y., Wells, J. M., Takebe, T.*
Featured in Nature Reviews
Featured in NIH Director’s Blog
Nature | 25 September
Koike et al. established a multi-organ connection in human stem cell derived organoid model amongst liver, biliary, pancreatic and duodenal tissues.
Koike, H., Iwasawa, K., Ouchi, R., Maezawa, M., Giesbrecht, K., Saiki, N., Ferguson A., Kimura, M., Thompson, W., Wells, J. M., Zorn, A. M. & Takebe, T.
Science | June 2019
Discussed current and future of designing complex organoids.
Takanori Takebe*, James M. Wells
ACS Nano | 4 December
Fang et al. designed a low-toxicity, photostable, near-infrared small molecule fluorescence probe HD-Br for use in the super-resolution imaging of lysosomes.
Fang, H., Yao, S., Chen,Q., Liu, C., Cai, Y., Geng, S., Bai, Y., Tian, Z., Zacharias, A. L., Takebe, T., Chen, Y., Guo, Z., He, W., and Diao, J.
2018
Stem Cell Reports | 9 October
Takahisa Matsuzaki, Shinya Matsumoto, Toshiharu Kasai, Hiroshi Y. Yoshikawa, Hideki Taniguchi, Takanori Takebe
Stem Cell Reports | September 2019
Hiroaki Ayabe, Takahisa Anada, Takuo Kamoya, Tomoya Sato, Masaki Kimura, Emi Yoshizawa, Shunyuu Kikuchi, Yasuharu Ueno, Keisuke Sekine, Gray Camp, Barbara Treutlein, Autumn Ferguson, Osamu Suzuki, Takanori Takebe, Hideki Taniguchi
iScience | 31 May
Masaki Kimura, Momoko Azuma, Ran-Ran Zhang, Wendy Thompson, Christopher N. Mayhew, Takanori Takebe
Cell Reports | 8 May
Yoshinobu Takahashi, Keisuke Sekine, Tatsuya Kin, Takanori Takebe, Hideki Taniguchi
Selected as cover article
Stem Cell Reports | 13 March
Ran-Ran Zhang, Masaru Koido, Tomomi Tadokoro, Rie Ouchi, Tatsuya Matsuno, Yasuharu Ueno, Keisuke Sekine, Takanori Takebe, Hideki Taniguchi
2017
Cell Reports | 5 December
Takanori Takebe, Keisuke Sekine, Masaki Kimura, Satoshi Okamoto, Yasuharu Ueno, Hideki Taniguchi
Cell Stem Cell | 7 September
Takanori Takebe, Boyang Zhang, Milica Radisic
Cell Stem Cell | Q&A | 1 June
Hans Clevers, Madeline Lancaster, and Takanori Takebe
Development | 14 March
Hiroyuki Koike, Ran-Ran Zhang, Yasuharu Ueno, Keisuke Sekine, Yun-Wen Zheng, Takanori Takebe, Hideki Taniguchi
Nature | 14 June
J. Gray Camp, Keisuke Sekine, Tobias Gerber, Henry Loeffler-Wirth, Hans Binder, Malgorzata Gac, Sabina Kanton, Jorge Kageyama, Georg Damm, Daniel Seehofer, Lenka Belicova, Marc Bickle, Rico Barsacchi, Ryo Okuda, Emi Yoshizawa, Masaki Kimura, Hiroaki Ayabe, Hideki Taniguchi, Takanori Takebe & Barbara Treutlein
2016
Developmental Biology | 15 December
Tadahiro Shinozawa, Hiroshi Y. Yoshikaw, Takanori Takebe
Reviews in Cell Biology and Molecular Medicine | November
Hiroyuki Koike, Tamir Rashid, Takanori Takebe
Cell Transplantation | 1 May
Shintaro Kagimoto, Takanori Takebe, Shinji Kobayashi, Yuichiro Yabuki, Ayaka Hori, Koichi Hirotomi, Taro Mikami, Toshimasa Uemura, Jiro Maegawa, Hideki Taniguchi
Regenerative Therapy | March
Yoshinobu Takahashi, Takanori Takebe, Hideki Taniguchi
Current Pathobiology Reports | 11 April
Hiroyuki Koike & Takanori Takebe
2015
Cell Stem Cell | 7 May
TakanoriTakebe, Masahiro Enomura, Emi Yoshizawa, Masaki Kimura, Hiroyuki Koike, Yasuharu Ueno, Takahisa Matsuzaki, Takashi Yamazaki, Takafumi Toyohara, Kenji Osafune, Hiromitsu Nakauchi, Hiroshi Y.Yoshikawa, Hideki Taniguchi
Selected as Cover Article
Best of Cell Stem Cell, 2015
News and Views in Cell Stem Cell
Featured in Nature Methods
Nature | News Feature | 29 July
Cassandra Willyard
2014
Journal of Clinical Investigation | 9 September
Takanori Takebe, Shinji Kobayashi, Hiromu Suzuki, Mitsuru Mizuno, Yu-Min Chang, Emi Yoshizawa, Masaki Kimura, Ayaka Hori, Jun Asano, Jiro Maegawa, and Hideki Taniguchi
Stem Cells and Development | 2 September
Rashid T, Takebe T, Nakauchi H.
STEM CELLS | 23 August
Mitsuru Mizuno, Shinji Kobayashi, Takanori Takebe, Hiroomi Kan, Yuichiro Yabuki, Takahisa Matsuzaki, Hiroshi Y. Yoshikawa, Seiichiro Nakabayashi, Lee Jeong Ik, Jiro Maegawa, Hideki Taniguchi
Organ Biology | 10 July
Yoshinobu Takahashi, Takanori Takebe, Hideki Taniguchi.
Stem Cells and Development | 26 June
Yun-Wen Zheng, Tomonori Tsuchida, Taiki Shimao, Bin Li, Takanori Takebe, Ran-Ran Zhang, Yu Sakurai, Yasuharu Ueno, Keisuke Sekine, Naoto Ishibashi, Makiko Imajima, Takuji Tanaka, and Hideki Taniguchi
Clinical Pharmacology & Therapeutics | 21 May
T Takebe, H Taniguchi.
Hepatology | 4 February
Hiroyuki Koike, Yasuharu Ueno, Takako Naito, Tomoya Shiina, Susumu Nakata, Rie Ouchi, Yuta Obana, Keisuke Sekine, Yun‐Wen Zheng, Takanori Takebe, Kyo‐ichi Isono, Haruhiko Koseki, Hideki Taniguchi
Nature Protocols | 23 January
Takanori Takebe, Ran-Ran Zhang, Hiroyuki Koike, Masaki Kimura, Emi Yoshizawa, Masahiro Enomura, Naoto Koike, Keisuke Sekine & Hideki Taniguchi
Organogenesis | 22 January
Takanori Takebe, Naoto Koike, Keisuke Sekine, Ryoji Fujiwara, Takeru Amiya, Yun-Wen Zheng & Hideki Taniguchi
Yokohama Medical Journal | January
T. Takebe, H. Taniguchi.
2013
Nature | 03 July
Takanori Takebe, Keisuke Sekine, Masahiro Enomura, Hiroyuki Koike, Masaki Kimura, Takunori Ogaeri, Ran-Ran Zhang, Yasuharu Ueno, Yun-Wen Zheng, Naoto Koike, Shinsuke Aoyama, Yasuhisa Adachi & Hideki Taniguchi
Selected as Breakthrough of the Year, 2013 in Science
Selected as World top 5 discovery in Discover magazineNews and Views in NatureFeatured in Science, Nature Medicine, Cell Stem Cell, Hepatology, Gastroenterology, Cell Research, etc…
Press in BBC, The Economist, Scientific American, The Guardian, etc…
Biomaterials | July
Hiroyasu Tanaka, Shin Tanaka, Keisuke Sekine, Sayaka Kita, Ai Okamura, Takanori Takebe, Yun-Wen Zheng, Yasuharu Ueno, Junzo Tanaka, Hideki Taniguchi
Organ Biology | 10 July
Takanori Takebe, Hideki Taniguchi.
2012
BMC Biotechnology | November
Hiroyuki Koike, Koji Kubota, Keisuke Sekine, Takanori Takebe, Rie Ouchi, Yun-Wen Zheng, Yasuharu Ueno, Naoki Tanigawa, Hideki Taniguchi
Transplantation Proceedings | July
T Takebe, N Koike, K Sekine, M Enomura, Y Chiba, Y Ueno, Y-W Zheng, H Taniguchi
Transplantation Proceedings | May
T Takebe, K Sekine, Y Suzuki, M Enomura, S Tanaka, Y Ueno, Y-W Zheng, H Taniguchi
2011
PLOS ONE | 19 October
Shinji Kobayashi ,Takanori Takebe ,Yun-Wen Zheng,Mitsuru Mizuno,Yuichiro Yabuki,Jiro Maegawa,Hideki Taniguchi
PNAS | 30 August
Shinji Kobayashi, Takanori Takebe, Midori Inui, Sayaka Iwai, Hiroomi Kan, Yun-Wen Zheng, Jiro Maegawa, and Hideki Taniguchi
Book
2019 | Takanori Takebe . Japan, Yodosha Co., Ltd.ISBN 978-4-7581-2239-9
2019 |Takanori Takebe (2019) , Japan, Yodosha, ISBN 978-4-7581-2500-0
November 2016 | Koike H, Takebe T*. Growing Mini-Organs from Stem Cells. Wiley-VCH. Volume 2
Issue 4.
July 2015 | Ran-Ran Zhang, Hiroyuki Koike, Takanori Takebe, ‘The Visualization of Human Organogenesis from Stem Cells by Recapitulating Multicellular Interactions’, p. 275-283, 15
Media
June 2020 | Takanori Takebe. Japan. PRESIDENT Inc.
February 2020 | Takanori Takebe . Japan. The Asahi Shimbun Company.
January 2020 | Takanori Takebe. Japan. Newton Press Ltd.
November 2019 | Takanori Takebe, Ken Iwasawa. Japan. Medical Principle Co., Ltd.